The Role of Antioxidants in the Management of Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric that has significant effect on the quality of life. The most effective treatment for OCD combination selective serotonin reuptake inhibitors (SSRI) with cognitive behavior therapy (CBT). However, several adverse effects have been linked this usual pharmacotherapy, and it unsuccessful in many patients. exact pathophysiology not completely known, though role oxidative stress its pathogenesis proposed recently. This review presents an overview animal human studies antioxidant OCD. use antioxidants against novel neurodegenerative disorders. Among antioxidants, NAC was one studied drugs OCD, showed improvement symptoms. Thus, could be promising as adjuvant limited number are conducted these agents, better judgment, large sample size necessary.